For more information, refer to the How to Clean Your Mouse section. Make sure the optical opening on the bottom of the mouse and around the scroll wheel is clean.Reseat the wired USB mouse cable into the USB port.
Note: The following steps apply to all brands of wired USB mice. Resolving Cursor and Scroll Wheel Issues for a Wired USB Mouse When the connector does not seem to fit, adjust the angle or flip it over. Note: The connector only goes in one way.